Create data.frame with dosing for usage in simulation with deSolve

This function creates a data.frame that can be used for events of a deSolve simulation

Usage

dose_func(cmt, value, tinf, tau, ndose, times)

Arguments

cmt: number of compartment or differential equation where the dosing should be given
value: the value of the dosing that should be given
tinf: in case value is set an infusion is assumed with tinf as infusion time
tau: dosing interval to be used
ndose: number of doses to be used
times: In case tau and ndose cannot be used (unequal dosing), this parameter can be used to set times of dosing (e.g c(0,24,168))

Value

a data frame that can be used as an event dataset within deSolve

Author

Richard Hooijmaijers

Examples


 dose_func(8,100,tau=48,ndose=5,tinf=2)
#>    var time value method
#> 1   A8    0    50    add
#> 6   A8    2     0    rep
#> 2   A8   48    50    add
#> 7   A8   50     0    rep
#> 3   A8   96    50    add
#> 8   A8   98     0    rep
#> 4   A8  144    50    add
#> 9   A8  146     0    rep
#> 5   A8  192    50    add
#> 10  A8  194     0    rep